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导师姓名:李言伟
性别:
人气指数:2580
所属院校:华南农业大学
所属院系:海洋学院
职称:副教授
导师类型:硕导
招生专业:水生生物学、水产养殖、渔业发展 、渔业发展(非全日制)
研究领域:

针对鱼类养殖业危害较严重的链球菌病和刺激隐核虫病,开展免疫防控机制和防控技术研究。

研究领域:

针对鱼类养殖业危害较严重的链球菌病和刺激隐核虫病,开展免疫防控机制和防控技术研究。 [收起]

通讯方式 :
电子邮件:yanweili@scau.edu.cn
通讯地址:广州市天河区五山路华南农业大学动科新楼103
个人简述 :
个人简介
李言伟博士、副教授、硕士生导师。近年先后主持国家自然基金、广东省自然科学基金、省级渔港建设和渔业发展专项资金等项目6项,参与国家自然基金和国家科技支撑计划项目各2项;发表SCI论文44篇,制定农业部水产行业标准1项,参编专著1部,申请国家发明专利14项,获得广东省科学技术二等奖1项。
获奖荣誉
“刺激隐核虫生物学及综合防控技术研究”获2014年度广东省科学技术奖二等奖(6/10)。
科研工作 :
工作经历
2015.07-至今,华南农业大学,海洋学院,副教授;
2012.07-2015.06,中山大学,生命科学学院,博士后。
科研项目
1.“海洋生物资源保护与利用粤港联合实验室”联合项目,防治刺激隐核虫病和虹彩病毒病中草药的筛选,2017.07-2018.06,在研,主持;
2.广东省动植物与食品进出口技术措施研究重点实验室开放课题,刺激隐核虫诊断技术的研发,2015.10-2017.09,在研,主持;
3.省级渔港建设和渔业发展专项资金,刺激隐核虫病的免疫防控试验,2016.05-2017.04,在研,主持;
4.国家自然科学基金,石斑鱼TLR9和TLR21信号通路及其抗病机制研究,2014.01-2016.12,已结题,主持;
5.广东省自然科学基金,石斑鱼TLR9和TLR21配体识别功能研究,2013.10-2015.10,已结题,主持;
6.博士后科学基金,石斑鱼TLR9/21重要功能结构域的晶体结构研究,2012.11-2014.11,已结题,主持;
7.国家自然科学基金,黄斑蓝子鱼对刺激隐核虫的天然抗性机制研究,2012.01-2015.12,已结题,参与;
8.国家自然科学基金,刺激隐核虫感染诱发的海水鱼类粘膜免疫反应研究,2009.01-2011.12,已结题,参与。
发表论文
YangM,ZhouL,WangHQ,LuoXC,DanXM,LiYW*.MolecularcloningandexpressionanalysisofCCL25anditsreceptorCCR9sfromEpinepheluscoioidespostCryptocaryonirritansinfection.FishShellfishImmunol.201767:402-410.(*通讯作者)
NiLY,ZhouL,WangHQ,LuoXC,DanXM,LiYW*.IdentificationandexpressionanalysisofthreeXCR1-likereceptorsfromEpinepheluscoioidesafterCryptocaryonirritansinfection.FishShellfishImmunology.2017:67,95-102.(*通讯作者)
LiZX1,LiYW1,XuS,XuY,MoZQ,DanXM,LuoXC.Grouper(Epinepheluscoioides)TCRsignalingpathwaywasinvolvedinresponseagainstCryptocaryonirritansinfection.FishShellfishImmunol.201764:176-184.(1共同第一)
JiangB,LiYW,HuYZ,LuoHL,LiAX.Characterizationandexpressionanalysisofsixinterleukin-17receptorgenesingrouper(Epinepheluscoioides)afterCryptocaryonirritansinfection.Fish&ShellfishImmunology.201769:46-51.
BaiJS,LiYW,DengY,HuangYQ,HeSH,DaiJ,ZhaoSZ,DanXM,LuoXC.MolecularidentificationandexpressionanalysisofTLR5MandTLR5Sfromorange-spottedgrouper(Epinepheluscoioides).FishShellfishImmunol.2017:63,97-102.
SunHY,HuangMZ,LiYW,HuangJH,MoZQ,ChenRA,DanXM.Twonovelp38MAPKsidentifiedfromEpinepheluscoioidesandtheirexpressionpatterninresponsetoCryptocaryonirritansinfection.FishShellfishImmunol.201767:459-466.
LiYW,ZhaoF,MoZQ,LuoXC,LiAX,DanXM.Characterization,expression,andfunctionalstudyofIRAK-1fromgrouper,Epinepheluscoioides.FishShellfishImmunol.201656:374-81.
LiYW,XuDD,LiX,MoZQ,LuoXC,LiAX,DanXM.IdentificationandcharacterizationofthreeTLR1subfamilymembersfromtheorange-spottedgrouper,Epinepheluscoioides.DevCompImmunol.201661:180-9.
JiangB,LiYW,AbdullahiAY,DanXM,GongH,KeQZ,LiAX,LiGQ.Placematandrotationalculturing:AnovelmethodtocontrolCryptocaryonirritansinfectionbyremovingtomonts.Aquaculture.2016459:84-8.
ZhangJ,WuXY,LiYW,XieMQ,LiAX.ThecompletemitochondrialgenomeofTetrancistrumnebulosi(Monogenea:Ancyrocephalidae).MitochondrialDNAPartA.201627:22-3.
SuYL,FengJ,LiYW,BaiJS,LiAX.DevelopmentofaquantitativePCRassayformonitoringStreptococcusagalactiaecolonizationandtissuetropisminexperimentallyinfectedtilapia.JFishDis.201639:229-38.
LiYW,WangZ,MoZQ,LiX,LuoXC,DanXM,LiAX.Grouper(Epinepheluscoioides)MyD88andTollip:Intracellularlocalizationandsignaltransductionfunction.FishShellfishImmunol.201542:153-8.
LiYW,LiX,WangZ,MoZQ,DanXM,LuoXC,LiAX.Orange-spottedgrouperEpinepheluscoioidesTak1:molecularidentification,expressionanalysisandfunctionalstudy.JournalofFishBiology.201586:417-30.
MoZQ,LiYW,ZhouL,LiAX,LuoXC,DanXM.Grouper(Epinepheluscoioides)IL-34/MCSF2andMCSFR1/MCSFR2wereinvolvedinmononuclearphagocytesactivationagainstCryptocaryonirritansinfection.FishShellfishImmunol.201543:142-9.
MoZQ,ChenRA,LiYW,HuangXZ,LiAX,LuoXC,DanXM.CharacterizationandexpressionanalysisoftwonovelCCR6chemokinereceptorsandtheirthreepotentialligandsCCL20Lsofgrouper(Epinepheluscoioides)postCryptocaryonirritansinfection.FishShellfishImmunol.201547:280-8.
MaiYZ,LiYW,LiRJ,LiW,HuangXZ,MoZQ,LiAX.ProteomicanalysisofdifferentiallyexpressedproteinsinthemarinefishparasiticciliateCryptocaryonirritans.VetParasitol.2015211:1-11.
ZhouLL,DanXM,LiYW,LiXX,ChenXL,LiY,GanL.Effectofreducing3.2%dietaryproteinlevelonthegrowthperformanceandimmunityofNiletilapia(Oreochromisniloticus)withsupplementationofmultiaminoacids.IranianJournalofFisheriesSciences.201514:997-1009.
ZhaoF,LiYW*,PanHJ,ShiCB,LuoXC,LiAX,WuSQ.TAK1-bindingproteins(TAB1andTAB2)ingrasscarp(Ctenopharyngodonidella):Identification,characterization,andexpressionanalysisafterinfectionwithIchthyophthiriusmultifiliis.Fish&ShellfishImmunology.201438:389-99.(*通讯作者)
LiYW,MoXB,ZhouL,LiX,DanXM,LuoXC,LiAX.IdentificationofIRAK-4ingrouper(Epinepheluscoioides)thatimpairsMyD88-dependentNF-κBactivation.Developmental&ComparativeImmunology.201445:190-7.
LiYW,LiuL,HuangPR,FangW,LuoZP,PengHL,WangYX,LiAX.ChronicstreptococcosisinNiletilapia,Oreochromisniloticus(L.),causedbyStreptococcusagalactiae.JournalofFishDiseases.201437:757-63.
LiYW,LiX,XiaoXX,ZhaoF,LuoXC,DanXM,LiAX.MolecularcharacterizationandfunctionalanalysisofTRAF6inorange-spottedgrouper(Epinepheluscoioides).Developmental&ComparativeImmunology.201444:217-25.
ZhangX1,LiYW1,MoZQ,LuoXC,SunHY,LiuP,LiAX,ZhouSM,DanXM.OutbreakofanoveldiseaseassociatedwithVibriomimicusinfectioninfreshwaterculturedyellowcatfish,Pelteobagrusfulvidraco.Aquaculture.2014432:119-24.(1共同第一作者)
YiT1,LiYW1,LiuL,XiaoXX,LiAX.ProtectionofNiletilapia(OreochromisniloticusL.)againstStreptococcusagalactiaefollowingimmunizationwithrecombinantFbsAandα-enolase.Aquaculture.2014428–429:35-40.(1共同第一作者)
LiuL1,LiYW1,HeRZ,XiaoXX,ZhangX,SuYL,etal.OutbreakofStreptococcusagalactiaeinfectioninbarcoogrunter,Scortumbarcoo(McCulloch&Waite),inanintensivefishfarminChina.JournalofFishDiseases.201437:1067-72.(1共同第一作者)
ZhaoF,LiYW,PanHJ,ShiCB,LuoXC,LiAX,WuSQ.TAK1-bindingproteins(TAB1andTAB2)ingrasscarp(Ctenopharyngodonidella):Identification,characterization,andexpressionanalysisafterinfectionwithIchthyophthiriusmultifiliis.FishShellfishImmunol.201438:389-99.
HuangXZ,LiYW,MaiYZ,LuoXC,DanXM,LiAX.MolecularcloningofNCCRP-1genefromorange-spottedgrouper(Epinepheluscoioides)andcharacterizationofNCCRP-1+cellspostCryptocaryonirritansinfection.DevCompImmunol.201446:267-78.
YinF,GongQY,LiYW,DanXM,SunP,GaoQX,ShiZH,PengSM,LiAX.EffectsofCryptocaryonirritansinfectiononthesurvival,feeding,respiratoryrateandionicregulationofthemarbledrockfishSebastiscusmarmoratus.Parasitol.2014141:279-86.
ZhangJ,WuXY,LiYW,ZhaoM,XieMQ,LiAX.ThecompletemitochondrialgenomeofNeobenedeniamelleni(Platyhelminthes:Monogenea):mitochondrialgenecontent,arrangementandcompositioncomparedwithtwoBenedeniaspecies.MolBiolRep.201441:6583-9.
ZhaoF,LiYW,PanHJ,WuSQ,ShiCB,LuoXC,LiAX.Grasscarp(Ctenopharyngodonidella)TRAF6andTAK1:MolecularcloningandexpressionanalysisafterIchthyophthiriusmultifiliisinfection.FishShellfishImmunol.201334:1514-23.
ZhaoF,LiYW,PanHJ,ShiCB,LuoXC,LiAX,WuSQ.Expressionprofilesoftoll-likereceptorsinchannelcatfish(Ictaluruspunctatus)afterinfectionwithIchthyophthiriusmultifiliis.FishShellfishImmunol.201335:993-7.
DanXM,ZhongZP,LiYW,LuoXC,LiAX.Cloningandexpressionanalysisofgrouper(Epinepheluscoioides)M-CSFRgenepostCryptocaryonirritansinfectionanddistributionofM-CSFR+cells.FishShellfishImmunol.201335:240-8.
DanXM,ZhangTW,LiYW,LiAX.Immuneresponsesandimmune-relatedgeneexpressionprofileinorange-spottedgrouperafterimmunizationwithCryptocaryonirritansvaccine.FishShellfishImmunol.201334:885-91.
LiYW,LuoXC,DanXM,QiaoW,HuangXZ,LiAX.Molecularcloningoforange-spottedgrouper(Epinepheluscoioides)TLR21andexpressionanalysispostCryptocaryonirritansinfection.Fish&ShellfishImmunology.201232:476-81.
HaoJ,LiYW,XieMQ,LiAX.Molecularcloning,recombinantexpressionandantibacterialactivityanalysisofhepcidinfromSimensiscrocodile(Crocodylussiamensis).CompBiochemPhysiolBBiochemMolBiol.2012163:309-15.
LiYW,LuoXC,DanXM,HuangXZ,QiaoW,ZhongZP,LiAX.Orange-spottedgrouper(Epinepheluscoioides)TLR2,MyD88andIL-1βinvolvedinanti-Cryptocaryonirritansresponse.Fish&ShellfishImmunology.201130:1230-40.
LiYW,DanXM,ZhangTW,LuoXC,LiAX.Immune-relatedgenesexpressionprofileinorange-spottedgrouperduringexposuretoCryptocaryonirritans.ParasiteImmunology.201133:679-987.
科研创新
(1)一种抗刺激隐核虫斜带石斑鱼苗种的生产方法技术.申请日期:2016.第三专利人.
(2)一种抗刺激隐核虫卵形鲳鲹苗种的生产方法技术.申请日期:2016.第三专利人.
(3)一种抗刺激隐核虫鮸鱼苗种的生产方法技术.申请日期:2016.第三专利人.
(4)一种抗刺激隐核虫紫红笛鲷苗种的生产方法技术.申请日期:2016.第三专利人.
(5)一种抗刺激隐核虫花尾胡椒鲷苗种的生产方法技术.申请日期:2016.第三专利人.
(6)一种抗刺激隐核虫大黄鱼苗种的生产方法技术.申请日期:2016.第三专利人.
(7)一种抗刺激隐核虫黑鲷苗种的生产方法技术.申请日期:2016.第三专利人.
(8)一种抗刺激隐核虫珍珠龙胆石斑鱼苗种的生产方法技术.申请日期:2016.第三专利人.
(9)一种抗刺激隐核虫巨石斑鱼苗种的生产方法.申请日期:2016.第三专利人.
(10)一种抗刺激隐核虫褐点石斑鱼苗种的生产方法.申请日期:2016.第三专利人.
(11)一种斜带石斑鱼CCR12的基因克隆和原核表达、纯化方法.申请日期:2017.第二专利人.
(12)一种斜带石斑鱼CCR12的多克隆抗体制备方法及其应用.申请日期:2017.第二专利人.
(13)一种刺激隐核虫亚单位疫苗的制备方法及其应用.申请日期:2017.第二专利人.
(14)一种刺激隐核虫表面蛋白C1多克隆抗体的制备方法及其应用.申请日期:2017.第一专利人.
教育背景 :
2007.09–2012.06,中山大学生命科学学院(硕博连读),水生生物学,博士;
2003.09–2007.06,东北农业大学生命科学学院,生物技术,学士。
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